EJVES Extra
Volume 17, Issue 2 , Pages 14-16 , February 2009

Cyclo-oxygenase-2 Inhibitors and Peripheral Thrombosis – A Case Report Demonstrating a Possible Adverse Effect

  • M. Chandra

      Affiliations

    • Pinderfields General Hospital, Wakefield, UK
    • Corresponding Author InformationCorrespondence to: Dr Manik Chandra, 120 Stanks Drive, Leeds LS14 5QD, UK. Tel.: +44 1132600053; mobile: +7730619990.
    • ,
  • P.J. Kent

      Affiliations

    • Leeds Vascular Institute, Leeds, UK

Received 26 June 2008 ,Accepted 7 November 2008.

References 

  1. Fitzgerald GA, Patrono C. The coxibs, selective inhibitors of cyclo-oxygenase-2. N Engl J Med. 2001;345:433–442
  2. Bombardier C, Laine L, Reicin A, Shapiro D, Burgos-Vargas R, Davis B, et al. Comparison of upper gastrointestinal toxicity of rofecoxib and naproxen in patients with rheumatoid arthritis. N Engl J Med. 2000;343:1520–1528
  3. Solomon SD, McMurray JJV, Pfeffer MA, Wittes J, Fowler R, Finn P, et al. Cardiovascular risk associated with celecoxib in a clinical trial for colorectal adenoma prevention. N Engl J Med. 2005;352:1071–1080
  4. Mukherjee D, Nissen SE, Topol EJ. Risk of cardiovascular events associated with selective COX-2 inhibitors. JAMA. 2001;286:954–959
  5. Konstantinopoulos PA, Lehmann DF. The cardiovascular toxicity of selective and nonselective cyclo-oxygenase inhibitors: comparisons, contrasts and aspirin confounding. J Clin Pharmacol. 2005;45:742–750
  6. Jain S, Bhatt P, Muralikrishna GK, Malhotra P, Kumari S, Varma S. Extensive arterial and venous thrombosis in a patient with ulcerative colitis – a case report. MedGenMed. 2005;7(2):10

PII: S1533-3167(08)00028-9

doi: 10.1016/j.ejvsextra.2008.11.002

EJVES Extra
Volume 17, Issue 2 , Pages 14-16 , February 2009

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