EJVES Extra
Volume 17, Issue 2 , Pages 14-16, February 2009

Cyclo-oxygenase-2 Inhibitors and Peripheral Thrombosis – A Case Report Demonstrating a Possible Adverse Effect

  • M. Chandra

      Affiliations

    • Pinderfields General Hospital, Wakefield, UK
    • Corresponding Author InformationCorrespondence to: Dr Manik Chandra, 120 Stanks Drive, Leeds LS14 5QD, UK. Tel.: +44 1132600053; mobile: +7730619990.
    • ,
  • P.J. Kent

      Affiliations

    • Leeds Vascular Institute, Leeds, UK

Received 26 June 2008; accepted 7 November 2008. published online 27 January 2009.

Abstract 

Cyclo-oxygenase-2 inhibitors are thought to be associated with an increased risk of cardiovascular events as a result of alteration in hemostasis. We report the case of a 39-year-old patient with minimal risk factors for cardiovascular disease who was prescribed a cyclo-oxygenase-2 inhibitor. He presented with symptoms of distal vessel thrombosis which was confirmed with angiography; this provides further evidence of the possible association of cyclo-oxygenase-2 inhibitors and thrombus formation.

Keywords: Cyclo-oxygenase 2 inhibitors, Thromboembolism, Peripheral vascular diseases, Adverse effects

 

PII: S1533-3167(08)00028-9

doi:10.1016/j.ejvsextra.2008.11.002

Refers to article:

  • Cyclo-oxygenase-2 Inhibitors and Peripheral Thrombosis—A Case Report Demonstrating a Possible Adverse Effect , 27 January 2009

    M. Chandra, P.J. Kent
    European Journal of Vascular & Endovascular Surgery April 2009 (Vol. 37, Issue 4, Page 495)

EJVES Extra
Volume 17, Issue 2 , Pages 14-16, February 2009

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