EJVES Extra
Volume 13, Issue 2 , Pages 23-25, February 2007

Arterial Occlusion from Anti-Jo1 Antibody-associated Autoimmune Myositis: Arteritis not Compartment Syndrome

  • M.J. Laugharne

      Affiliations

    • Department of Surgery, North Bristol NHS Trust, Bristol, UK
    • Corresponding Author InformationCorresponding author. Mr M.J. Laugharne, Department of Surgery, Southmead Hospital, North Bristol NHS Trust, Westbury-on-Trym, Bristol BS10 5NB, UK.
  • ,
  • J.J. Wood

      Affiliations

    • Department of Surgery, North Bristol NHS Trust, Bristol, UK
  • ,
  • D.C. Mitchell

      Affiliations

    • Department of Surgery, North Bristol NHS Trust, Bristol, UK
  • ,
  • S.C. Glover

      Affiliations

    • Department of Infectious Diseases, Immunology and General Medicine, North Bristol NHS Trust, Bristol, UK

Accepted 14 October 2006.

We present a case of arterial occlusion secondary to polymyositis associated with anti-Jo1 antibodies. A 44 year old lady presented with thigh pain and myositis associated with anti-Jo1 antibody positivity. She developed critical lower limb ischaemia with normal compartment pressures but occlusive disease on angiography. Management was with steroids and methotrexate with amputation of three digits. This case illustrates adult arteritis in the presence of acute polymyositis and anti-Jo1 antibodies as a rare yet diagnostically challenging cause of arterial ischaemia.

Keywords: Arterial occlusive diseases, Arteritis, Jo-1 antibody, Autoimmune disease, Polymyositis

 

PII: S1533-3167(06)00086-0

doi:10.1016/j.ejvsextra.2006.10.004

Refers to article:

  • Arterial Occlusion from Anti-Jo1 Antibody-Associated Autoimmune Myositis: Arteritis not Compartment Syndrome , 30 December 2006

    M.J. Laugharne, J.J. Wood, D.C. Mitchell, S.C. Glover
    European Journal of Vascular & Endovascular Surgery March 2007 (Vol. 33, Issue 3, Page 377)

EJVES Extra
Volume 13, Issue 2 , Pages 23-25, February 2007